Ta yaya Glycerylphosphocholine Zai Ƙarfafa Ƙarfin Ƙwaƙwalwar ku?

Glycerylphosphocholine (GPC, kuma aka sani da L-alpha-glycerylphosphosphocholine ko alphacholine)asalin tushen choline ne da ke samuwa a cikin abinci iri-iri (ciki har da madarar nono) kuma a cikin dukkanin kwayoyin halittar dan adam Ya ƙunshi ƙananan choline. GPC kwayar halitta ce mai narkewar ruwa wacce aka nuna ta zama tushen tushen choline na asibiti fiye da choline ko phosphatidylcholine (PC) daga abinci ko kari.

GPC da ake gudanarwa ta baki yana tsotsewa sosai kuma an raba shi a cikin enterocytes cikin glycerol-1-phosphate da choline. Bayan shan GPC, matakan choline a cikin plasma ya tashi da sauri kuma ya kasance mai girma na awanni 10. Babban matakin maida hankali kan plasma na choline yana ƙarfafa ingantaccen jigilar sa ta shingen kwakwalwar jini. Wannan yana ƙara shagunan choline a cikin neurons, inda ake amfani dashi don haɗa PC da acetylcholine.

A tsari, α-GPC wani fili ne na choline da ke daure zuwa kwayoyin glycerol ta hanyar rukunin phosphate, kuma choline ne mai dauke da phospholipid. Abubuwan da ke cikin choline yana da girma sosai, yana lissafin kusan 40%, wanda ke nufin cewa 1000 MG na α-GPC na iya samar da kimanin 400 MG na choline kyauta.

Choline shine sinadari mai mahimmanci da ake samu a cikin kayan kiwo da ƙwai waɗanda ke taimaka wa sel su kula da membranes. Choline kanta ma wajibi ne don yin acetylcholine. Duk da yake alpha-GPC da sauran choline irin su phosphatidylcholine da lecithin na iya inganta samar da acetylcholine, alpha-GPC ya fi kyau a zahiri saboda lipids da yake bayarwa a zahiri yana sauƙaƙa wa sel su sha, Fiye da 90% na phosphatidylcholine yana sha da tasoshin lymphatic. , yayin da α-GPC galibi ana shayar da shi ta hanyar portal vein, don haka haɓakar haɓaka ya fi girma, don haka yana haɓaka samar da acetylcholine yadda ya kamata. Acetylcholine ne neurotransmitter wanda ke taka muhimmiyar rawa wajen daidaita aikin kwakwalwa da sarrafa tsoka. Kodayake zamu iya cinye choline ta hanyar abinci, adadin acetylcholine yana raguwa da shekaru.

Fa'idodin GPC-Bincike

Aikin kwakwalwa

• Inganta ƙwaƙwalwar ajiya, maida hankali da lokacin amsawa a cikin manya da kanana
• Yana haɓaka samarwa da sakin acetylcholine (ACh) daga neurons da yiwuwar wasu sel.
• Yana iya rama raguwar ACh da ke haifarwa ta hanyar tsufa, rashi isrogen (menopause, da yuwuwar amfani da maganin hana haihuwa na baka)
• Inganta tsarin EEG
• Ƙara samar da dopamine, serotonin da GABA18.
• Inganta aikin mitochondrial yayin ischemia / damuwa na oxidative
• Yana magance raguwar shekaru a cikin ƙwayoyin kwakwalwa da lambobin masu karɓa na ACh, aikin tsoka da samar da hormone girma
• Haɓaka fitowar hormone girma a cikin matasa da tsofaffi
• Ƙara yawan iskar oxygen, ƙarfin tsoka da lokacin amsawa, mai yiwuwa inganta daidaituwa, musamman a cikin tsofaffi.

Gyaran Kwakwalwa da Tallafin Alzheimer/Dementia

• Yana inganta farfadowar kwakwalwa bayan bugun jini, raunin kwakwalwa, da kuma maganin sa barci (kafin da bayan tiyata).
• Gyara nama mai shinge na jini-kwakwalwa da hauhawar jini ya lalace
• Inganta fahimta da halayyar zamantakewa a cikin cutar Alzheimer, jijiyar jijiyoyin jini / tsofaffi, da cutar Parkinson.
• Rage raguwar ƙarar kwakwalwa kamar cutar Alzheimer
• Yana iya zama da amfani a cikin cututtuka da ke buƙatar gyaran myelin da Duchenne muscular dystrophy Choline ayyuka a cikin jikin mutum da GPC.

Musamman kaddarorin a matsayin tushen mai ƙarfi na choline, toshe ginin acetylcholine da wani abu wanda ke haɓaka haɓakarsa da ɓoyewar sa.

• Acetylcholine ne neurotransmitter a cikin kwakwalwa da kuma sigina transducer a wani wuri a cikin jiki, m ga tsoka tsoka, sautin fata, gastrointestinal motsi, da sauran nama ayyuka. Ba kamar choline / PC da aka bayar ta hanyar abinci ko kari ba, an nuna ƙarin GPC yana da tasiri mai mahimmanci akan haɗin ACh da sakinsa daga ƙwayoyin cholinergic.

Ƙarin sakamako na GPC a cikin ingantaccen siginar cholinergic a cikin neurons da sauran kwayoyin halitta waɗanda zasu iya samar da acetylcholine. Wannan yana da fa'ida musamman lokacin da adadin da ingantaccen aiki na ƙananan ƙwayoyin cuta na cholinergic ya ragu saboda tsufa na yau da kullun ko matakai daban-daban na degenerative. Ƙarfafawa tare da GPC yana da yuwuwar ramawa kaɗan don waɗannan lahani saboda yana haifar da saurin haɓakar choline na plasma, wanda ke haifar da tasiri mai ƙarfi akan enzymes da masu jigilar kayayyaki a waɗannan hanyoyin.

Ginin gini na phosphatidylcholine (PC)

• PC na cikin phospholipids kuma muhimmin abu ne na membranes cell da membranes mitochondrial. Ƙarfin haɓakar GPC don taimakawa wajen dawo da bugun jini, da kuma magance raguwar shekaru masu yawa a cikin adadin masu karɓa na ACh a cikin ƙwayoyin jijiya ko kwakwalwa, ƙarin shaida ne na gudummawar da yake bayarwa ga kula da ƙwayar ƙwayar cuta ta hanyar PC.

Samuwar sphingomyelin

• Sphingomyelin wani bangare ne na kumfa na myelin wanda ke rufewa da kuma hana ƙwayoyin cuta da jijiyoyi. Sabili da haka, ƙarin GPC na iya zama da amfani a kowane yanayi tare da ƙara yawan buƙatar gyaran myelin, irin su neuropathy, sclerosis da yawa, da sauran yanayi da suka shafi lalata da kuma autoimmunity na nama mai juyayi. Jirgin kitse a ciki da wajen sel

• PC ya zama dole don haɓakawa da ɓoye ƙwayoyin VLDL. Triglycerides suna barin hanta a cikin barbashi na VLDL, wanda ke bayanin dalilin da yasa rashi choline yana ƙara haɗarin cututtukan hanta mai ƙima. Ana iya samun PC daga tushen abinci ko kari; duk da haka, PC don phospholipids da lipoproteins ba a samun su kai tsaye daga PC ɗin da aka ci ko riga-kafi. An haɗe ta daga magabatan choline daban-daban (ciki har da GPC), don haka shigar da PC ba lallai ba ne hanya mafi inganci don haɓaka tafkin PC na jiki.
Taimakawa motsin maniyyi

• GPC shine maɓalli mai mahimmanci a cikin abin da aka makala na DHA (docosahexaenoic acid), yin PC-DHA. Ana amfani da hadadden DHA-PC a cikin nau'ikan tantanin halitta masu aiki sosai kamar ƙwayoyin ji na hasken ido da ƙwayoyin maniyyi. DHA-PC yana ƙara yawan ruwa na membrane, wanda ke da mahimmanci ga aikin maniyyi mai lafiya. Maniyyi ya ƙunshi babban adadin GPC; Kwayoyin epididymal waɗanda ke noma ƙwayoyin maniyyi ana fitar da su daga tafkin GPC kuma suna haɗa PC-DHA. Ƙananan matakan GPC da PC-DHA a cikin maniyyi na iya ƙara haɗarin raguwar motsin maniyyi.

Kwatanta GPC da Acetyl-L-Carnitine (ALCAR)

• A cikin nazarin marasa lafiya da cutar Alzheimer ta ci gaba, GPC ya haifar da haɓaka mafi girma a cikin mafi yawan sigogi na neuropsychological idan aka kwatanta da ALCAR. Duk da yake duka mahadi suna goyan bayan karuwa a cikin acetylcholine, ana iya tunanin cewa za'a iya samun tasirin haɗin gwiwa tsakanin haɓaka mahaɗan guda biyu, kamar yadda GPC ke ba da choline yayin da ALCAR ke samar da bangaren acetyl don haɗakar acetylcholine.

Yiwuwar daidaitawa tsakanin GPC da kwayoyi. Ba a tsammanin ƙarin GPC zai yi mummunan tsoma baki tare da kowane magunguna da aka tsara don inganta aikin kwakwalwa. A zahiri, saboda fa'idodinsa akan hanyoyin cholinergic da haɓaka aikin membrane na sel neuronal, yana iya haɓaka fa'idodin su. GPC na iya haɓaka tasirin acetylcholinesterase AChE masu hanawa saboda yana iya ƙara adadin ACh a cikin ɓangarorin synaptic, yayin da waɗannan kwayoyi suna rage raguwar ta.

Bugu da ƙari, bisa ga nazarin dabba, GPC na iya haɓaka samar da dopamine, serotonin, ko GABA a cikin kwakwalwa, kuma GPC na iya inganta tasirin masu hana sake dawowa na waɗannan masu rarrabawa.

Suzhou Myland Pharm & Nutrition Inc.is mai sana'a ne mai rijista na FDA wanda ke ba da inganci mai inganci da tsaftar Alpha GPC foda.

A Suzhou Myland Pharm mun himmatu wajen samar da ingantattun kayayyaki a farashi mafi kyau. Mu Alpha GPC foda an gwada shi da ƙarfi don tsabta da ƙarfi, yana tabbatar da samun ƙarin ƙarin inganci da za ku iya dogara. Ko kuna son tallafawa lafiyar salula, haɓaka tsarin rigakafi ko haɓaka lafiyar gabaɗaya, mu Alpha GPC foda shine mafi kyawun zaɓi.

Tare da shekaru 30 na gwaninta da haɓaka ta hanyar fasaha mai zurfi da ingantattun dabarun R&D, Suzhou Myland Pharm ya haɓaka kewayon samfuran gasa kuma ya zama ƙarin ƙarin ilimin kimiyyar rayuwa, haɗin al'ada da kamfanin sabis na masana'antu.

Bugu da kari, Suzhou Myland Pharm kuma masana'anta ce mai rijista ta FDA. Abubuwan R&D na kamfanin, wuraren samarwa, da kayan aikin nazari na zamani ne kuma masu aiki da yawa, kuma suna iya samar da sinadarai daga milligrams zuwa ton a sikelin, kuma suna bin ka'idodin ISO 9001 da ƙayyadaddun samarwa GMP.