A cikin duniyar abinci mai gina jiki, nicotinamide riboside chloride (NRC) ya sami kulawa sosai don yuwuwar fa'idodinsa wajen haɓaka lafiyar salula da tsawon rai. Duk da haka, tare da kasuwar ambaliya tare da alamu da ƙira, zabar foda mai inganci na NRC na iya zama mai ban tsoro. Zaɓin ingancin nicotinamide riboside chloride foda a farkon wuri yana buƙatar yin la'akari da tsabta, tsarawa, ra'ayoyin abokin ciniki, da farashi. Ta hanyar ba da fifiko ga waɗannan abubuwan, zaku iya zaɓar samfuran da aka yi niyya waɗanda suke da inganci kuma suna tallafawa kasuwancin ku amintacce.
Nicotinamide riboside chloride shine nau'in gishiri na chloride na nicotinamide riboside (NR). NR wani labari ne na pyridine nucleoside na bitamin B3 wanda ke aiki a matsayin farkon nicotinamide adenine dinucleotide (NAD) ko NAD +. Nicotinamide riboside chloride shine nau'in crystalline na nicotinamide riboside (NR) chloride. Nicotinamide riboside chloride yana haɓaka matakan NAD [+] kuma yana kunna SIRT1 da SIRT3, a ƙarshe yana haɓaka metabolism na oxidative da kuma hana rashin daidaituwa na rayuwa wanda ke haifar da abinci mai mai yawa. Ana amfani da Nicotinamide riboside chloride a cikin abubuwan abinci.
Nicotinamide riboside chloride shine nau'in da aka saba amfani dashi a cikin kari kuma shine ingantaccen sigar NR. Siffar gishirin chloride yana haɓaka kwanciyar hankali da kasancewar NR, yana sa ƙarin ƙarin tasiri. Nicotinamide Riboside Chloride an samar da shi ta hanyar roba don tabbatar da daidaito, tsabta, da ƙarfi waɗanda ke da mahimmanci ga inganci da amincin sa.
NR wani nau'i ne na bitamin B3 (niacin) da kuma mafarinnicotinamide adenine dinucleotide (NAD+),mabuɗin coenzyme da ake samu a cikin dukkan sel masu rai da mahimmanci ga rayuwa. Dinucleotide ne, wanda ke nufin ya ƙunshi nucleotides guda biyu waɗanda ƙungiyar phosphate ke haɗe. Ɗayan nucleotide ya ƙunshi tushen adenine kuma ɗayan ya ƙunshi nicotinamide. NAD + shine ɗayan mafi yawan ƙwayoyin ƙwayoyin cuta a cikin jiki kuma muhimmin yanki na binciken tsufa.
NAD + shine mai don yawancin mahimman hanyoyin nazarin halittu:
1. Mayar da abinci mai gina jiki zuwa makamashi
2. Gyara lalacewar DNA
3. Ƙarfafa tsarin tsaro na tantanin halitta
4. Daidaita zaren circadian
Abin takaici, yayin da muke tsufa, matakan NAD+ suna raguwa, yana barin ƙarancin kuzari don aikin salula. Wannan na iya haifar da ci gaban cututtuka daban-daban masu alaƙa da shekaru kamar su ciwon sukari,
Matsakaicin adadin NR yana faruwa ta dabi'a a wasu abinci. Madara, yisti, da wasu abinci sun ƙunshi NR, amma a cikin ƙananan adadi. Misali, madara ya ƙunshi NR, amma kuna buƙatar cinye adadi mai yawa don isa matakan da aka yi amfani da su a cikin karatun asibiti. Saboda haka, ko da yake NR yana faruwa ta dabi'a, samun yawan adadin NR ta hanyar abinci kawai yana da kalubale.
Ganin wahalar samun isassun NRC daga tushen halitta, an haɓaka hanyoyin haɗa NRC. Samar da kayan aikin roba na NRC ya ƙunshi jerin halayen sinadaran da ke canza kayan farawa zuwa mahaɗan da ake so. Wannan tsari na iya samar da isassun adadin NRC don bincike da sakewa.
Nicotinamide riboside (NR) wani nau'i ne na bitamin B3, wanda kuma aka sani da niacin. Shi ne mafarin nicotinamide adenine dinucleotide (NAD +), coenzyme da ke cikin dukkanin sel masu rai kuma yana taka muhimmiyar rawa wajen gyaran makamashi da gyaran sel. muhimmiyar rawa. Matakan NAD + a dabi'a suna raguwa tare da shekaru, yana haifar da raguwar aikin tantanin halitta da haɓaka haɗarin cututtukan da ke da alaƙa da shekaru. Nicotinamide riboside chloride wani tsayayyen nau'i ne na NR kuma ana amfani dashi akai-akai a cikin abubuwan abinci don haɓaka matakan NAD + a cikin jiki.
Rage matakan NAD + alama ce ta tsufa kuma ana danganta su da nau'ikan cututtukan da suka shafi shekaru, gami da rikice-rikice na rayuwa, cututtukan neurodegenerative, da matsalolin zuciya. Ta hanyar haɓaka matakan NAD +, NRC tana da yuwuwar haɓaka aikin tantanin halitta da haɓaka tsufa. Anan ga wasu mahimman hanyoyin NRC na iya shafar tsarin tsufa:
1. Yana haɓaka samar da makamashin salula: NAD + yana da mahimmanci ga aikin mitochondria, ma'auni na sel waɗanda ke samar da makamashi. Ta hanyar haɓaka matakan NAD +, NR yana haɓaka aikin mitochondrial, ta haka yana haɓaka samar da makamashi da inganta lafiyar salula.
2. Gyaran DNA da kiyayewa: NAD + shine muhimmin sashi na tsarin gyaran DNA. Tarin lalacewar DNA tare da shekaru na iya haifar da rashin aiki na salula da kuma ci gaban cututtukan da suka shafi shekaru. Kariyar NR na iya tallafawa hanyoyin gyaran DNA, taimakawa wajen kula da kwanciyar hankali na kwayoyin halitta da kuma rage hadarin cututtuka.
3. Kunna Sirtuin: Sirtuin iyali ne na furotin da ke taka muhimmiyar rawa wajen daidaita lafiyar salula da tsawon rayuwa. Ana buƙatar NAD + don kunna Sirtuins, don haka inganta gyaran sel, anti-danniya da tsarin rayuwa. Ta hanyar haɓaka matakan NAD +, NR na iya haɓaka ayyukan sirtuin da tallafawa tsufa mai kyau.
Bincike na farko a cikin nau'ikan dabbobi ya nuna cewa kari na NR na iya tsawaita rayuwa, inganta lafiyar rayuwa, da haɓaka aikin fahimi. Gwajin asibiti na ɗan adam kuma sun nuna sakamako masu ban sha'awa, tare da ƙarin NR yana haɓaka matakan NAD +, haɓaka alamun lafiya na rayuwa, da haɓaka aikin jiki.
Wani sanannen binciken da aka buga a cikin mujallar Cell Metabolism ya gano cewa karin NR a cikin tsofaffi ya kara yawan matakan NAD + da inganta aikin tsoka da jimiri. Wani binciken da aka buga a Nature Communications ya ruwaito cewa NR supplementation inganta fahimi aiki da kuma rage neuroinflammatory alamomi a cikin wani linzamin kwamfuta model na cutar Alzheimer.
1. Inganta samar da makamashin salula
A tsakiyar sel mu su ne mitochondria, sau da yawa ana kiranta da "masu wutar lantarki" na tantanin halitta. Wadannan gabobin suna da alhakin samar da adenosine triphosphate (ATP), kudin makamashi na farko na tantanin halitta. Nicotinamide riboside chloride yana taka muhimmiyar rawa a cikin wannan tsari ta hanyar haɓaka matakan nicotinamide adenine dinucleotide (NAD +), coenzyme mai mahimmanci don aikin mitochondrial.
NAD+matakan a zahiri suna raguwa yayin da muke tsufa, wanda ke haifar da raguwar samar da makamashin salula da ƙara gajiya. Haɓakawa tare da NRC yana taimakawa dawo da matakan NAD +, ta haka yana haɓaka aikin mitochondrial da haɓaka samar da makamashi gaba ɗaya. Wannan yana inganta aikin jiki, yana rage gajiya kuma yana ƙara kuzari.
2. Taimakawa tsufa lafiya
Bincike ya nuna cewa kiyaye mafi kyawun matakan NAD + yana da mahimmanci ga tsawon rai da lafiyar gaba ɗaya. NAD + yana da hannu a cikin matakai daban-daban na salon salula, gami da gyaran DNA, maganganun kwayoyin halitta, da martanin damuwa na salon salula.
Ta hanyar haɓaka matakan NAD +, NRC na iya taimakawa kare sel daga lalacewa, haɓaka gyaran DNA, da tallafawa hanyoyin kariya na halitta don hana raguwar shekaru. Wannan na iya inganta lafiyar fata, rage alamun tsufa, da rage haɗarin cututtukan da suka shafi shekaru kamar cutar Alzheimer da Parkinson.
3. Haɓaka aikin fahimi
Rashin hankali shine matsala gama gari yayin da muke tsufa, amma nicotinamide riboside chloride na iya ba da mafita. NAD + yana da mahimmanci ga lafiyar kwakwalwa saboda yana tallafawa aikin neuron, yana kare kariya daga neurodegeneration, kuma yana inganta samar da neurotransmitter. Ƙarawa tare da NRC na iya inganta aikin fahimi, haɓaka ƙwaƙwalwar ajiya, da hana raguwar fahimi masu alaƙa da shekaru. Ta hanyar haɓaka matakan NAD +, NRC yana taimakawa kula da lafiya da aikin ƙwayoyin kwakwalwa, don haka inganta tsabtar tunani, maida hankali, da aikin fahimi gabaɗaya.
4. Inganta lafiyar jiki
Lafiyar ƙwayar cuta shine muhimmin al'amari na lafiyar gaba ɗaya, kuma an nuna nicotinamide riboside chloride yana da tasiri mai kyau akan metabolism. NAD + yana shiga cikin matakai na rayuwa iri-iri, gami da glucose da metabolism na lipid, hankalin insulin, da kashe kuzari. Haɓakawa tare da NRC na iya inganta lafiyar rayuwa ta hanyar haɓaka matakan NAD +, don haka haɓaka aikin hanyoyin hanyoyin rayuwa. Wannan na iya inganta sarrafa sukarin jini, rage haɗarin cututtukan rayuwa kamar su ciwon sukari, da ba da izinin sarrafa nauyi mafi kyau.
5. Taimakawa lafiyar zuciya da jijiyoyin jini
Lafiyar zuciya da jijiyoyin jini wani yanki ne na mayar da hankali ga nicotinamide riboside chloride. NAD + tana taka muhimmiyar rawa wajen kiyaye lafiya da aikin tsarin jijiyoyin jini, gami da zuciya da tasoshin jini. Ƙarin NRC na iya inganta lafiyar zuciya da jijiyoyin jini ta hanyar ƙara matakan NAD +, wanda ke taimakawa wajen hana damuwa na oxyidative, kumburi, da kuma rashin aiki na endothelial. Wannan yana inganta kwararar jini, yana rage haɗarin cututtukan zuciya, kuma yana inganta lafiyar zuciya gaba ɗaya.
Ana canza NRC zuwa NAD+ ta hanyar jerin halayen halayen halitta. Wannan tsari yana da inganci idan aka kwatanta da sauran abubuwan da suka faru na NAD+ kamar niacin da nicotinamide. Bincike ya nuna cewa kari na NRC zai iya ƙara haɓaka matakan NAD + yadda ya kamata, yana haifar da ingantaccen aikin mitochondrial, haɓaka samar da makamashi da ingantattun hanyoyin gyaran sel.
Yadda NR ke kwatanta da sauran kari
1. NR vs. Kariyar Vitamin B3 na Gargajiya
An yi amfani da kariyar bitamin B3 na gargajiya irin su niacin da niacinamide shekaru da yawa don tallafawa lafiyar zuciya da jijiyoyin jini da ƙananan matakan cholesterol. Duk da haka, su ma suna da wasu rashin amfani. Alal misali, niacin na iya haifar da ruwa, wani sakamako na yau da kullun wanda ke nuna ja da dumin fata. Niacinamide, a gefe guda, baya haifar da ruwa, amma ba shi da tasiri a haɓaka matakan NAD + fiye da NRC.
NRC ta fito a matsayin madaidaicin madadin saboda ikonta na haɓaka matakan NAD+ yadda ya kamata ba tare da haifar da lahani marasa daɗi da ke tattare da niacin ba. Wannan ya sa NRC ta zama zaɓi mai ban sha'awa ga waɗanda ke neman fa'idodin bitamin B3 ba tare da lahani ba.
2. NR da Coenzyme Q10 (CoQ10)
Coenzyme Q10 (CoQ10) wani sanannen kari ne wanda aka sani don rawar da yake takawa a samar da makamashi da kaddarorin antioxidant. Coenzyme Q10 yana da mahimmanci ga aikin mitochondria, ma'aunin wutar lantarki na tantanin halitta. Duk da yake ƙarin CoQ10 na iya tallafawa lafiyar mitochondrial da magance matsalolin iskar oxygen, ba ya shafar matakan NAD + kai tsaye.
NRC, a gefe guda, yana haɓaka matakan NAD + kai tsaye, ta haka yana haɓaka aikin mitochondrial da samar da makamashi. Ta hanyar haɓaka matakan NAD +, NRC tana ba da cikakkiyar hanya ga lafiyar salula da makamashin makamashi fiye da CoQ10 kadai.
3. NRC da Resveratrol
Resveratrol shine polyphenol da ake samu a cikin jan giya, inabi da wasu berries. An san shi don maganin antioxidant da anti-inflammatory Properties. Resveratrol ya shahara saboda yuwuwar sa don kunna sirtuins, dangin sunadaran da ke da alaƙa da lafiyar salula da tsawon rai. Duk da haka, resveratrol yana da ƙarancin bioavailability, ma'ana cewa ɗan ƙaramin yanki ne kawai na mahaɗin da aka cinye kuma jiki yana amfani dashi.
Ta hanyar haɓaka matakan NAD +, NRC kuma tana kunna sirtuins, don haka haɓaka fa'idodi iri ɗaya ga resveratrol. Bugu da ƙari, NR's m bioavailability yana tabbatar da mafi girma rabo na kari ana amfani da shi yadda ya kamata ta jiki, yana mai da shi mafi inganci zaɓi don tallafawa lafiyar salula da tsawon rai.
4. NRC da Antioxidant kari
Abubuwan da ake amfani da su na antioxidant, kamar bitamin C, bitamin E, da glutathione, ana amfani da su sosai don magance matsalolin iskar oxygen da kare sel daga lalacewa. Duk da yake waɗannan antioxidants suna taka muhimmiyar rawa wajen kawar da radicals kyauta, ba sa magance raguwar matakan NAD + da ke da alaƙa da tsufa.
NRC yana da fa'ida ta musamman na ba wai kawai tallafawa kariyar antioxidant ba, har ma da haɓaka matakan NAD +, waɗanda ke da mahimmanci don gyaran sel da kiyayewa. Ta hanyar magance matsalolin oxidative da raguwar NAD +,NRC yana ba da cikakkiyar hanya don inganta lafiyar gaba ɗaya da tsawon rai.
Me yasa inganci yana da mahimmanci
Tasirin kari na NRC ya dogara da ingancinsa. Samfuran marasa inganci na iya ƙunsar ƙazanta, ba a yi musu allurai ba, ko kuma suna da tsarin da ba su da inganci wanda zai rage amfanin su ko ma yana da illa. Sabili da haka, saka hannun jari a cikin babban ingancin nicotinamide riboside chloride foda yana da mahimmanci don cimma fa'idodin kiwon lafiya da ake so.
Mabuɗin abubuwan da za a yi la'akari
1. Tsafta da Karfi
Tsaftar Nicotinamide Riboside Chloride foda yana da mahimmanci. Nemo samfuran da ke ba da Takaddun Takaddun Bincike na ɓangare na uku (CoA). Wannan takaddun yana tabbatar da tsabta da ƙarfin samfurin, yana tabbatar da ya ƙunshi ƙayyadadden adadin NR kuma ba shi da gurɓata masu cutarwa. Da kyau, abun cikin NR ya kamata ya zama aƙalla 98% mai tsabta.
2. Tufafi da Ayyukan Masana'antu
Tushen albarkatun ƙasa da hanyoyin masana'anta da ake amfani da su na iya tasiri sosai ga ingancin nicotinamide riboside chloride foda. Zaɓi samfuran da suka fito daga mashahuran dillalai kuma ana ƙera su a wuraren da ke bin Kyawawan Ayyukan Masana'antu (GMP). Waɗannan ƙa'idodi suna tabbatar da samar da samfuran a cikin tsabtataccen yanayi mai sarrafawa wanda ke rage haɗarin gurɓatawa.
3. Bioavailability
Bioavailability yana nufin iyaka da ƙimar abin da jiki ke sha da amfani da wani sashi mai aiki. Wasu nau'ikan nicotinamide riboside chloride an ƙera su don haɓaka bioavailability, yana sa ya fi tasiri. Nemo samfuran da ke amfani da tsarin isarwa na ci gaba, irin su liposome encapsulation ko ci gaba da fasahar sakewa, don haɓaka sha.
4. Additives da fillers
Yawancin abubuwan kari sun ƙunshi abubuwan ƙarawa da filaye waɗanda za su iya tsoma abubuwan da ke aiki ko haifar da mummunan halayen. Zaɓi nicotinamide riboside chloride foda tare da ƙaramar ko babu ƙari don tabbatar da samun samfur mai tsabta da inganci. Idan additives sun kasance, ya kamata a jera su a fili kuma amintacce don cinyewa.
5. Brand suna da kuma sake dubawa
Sunan alamar yana iya ba da haske mai mahimmanci game da ingancin samfuransa. Bincika tarihin alamar, sake dubawa na abokin ciniki, da kowane takaddun shaida ko lambobin yabo da ya samu. Ingantacciyar amsa da tallafi daga amintattun kwararrun kiwon lafiya sun nuna cewa samfurin abin dogaro ne.
6. Farashin da daraja
Duk da yake farashin bai kamata ya zama abin yanke hukunci kawai ba, yana iya zama alamar inganci. Matsakaicin ƙarancin farashi na foda na roba na halitta na iya lalata tsabta da ƙarfi. Kwatanta farashin daga sanannun samfuran, la'akari da farashin kowane sabis da ƙimar gaba ɗaya. Zuba jari a cikin ɗan ƙaramin tsada, samfur mai inganci na iya haifar da kyakkyawan sakamako a cikin dogon lokaci.
Matakai masu Aiki don Zaɓin Ingantacciyar Nicotinamide Riboside Chloride Foda
Mataki 1: Bincike da Zaɓuɓɓuka
Fara da bincike daban-daban NRC foda brands da dabaru. Ƙirƙiri jerin jerin samfuran da suka dace da mahimman abubuwan da aka jera a sama. Yi amfani da albarkatun kan layi kamar tarukan kiwon lafiya, shafukan bita, da shawarwarin masana don tattara bayanai.
Mataki na 2: Tabbatar da Tsafta da Ƙarfi
Bincika ko samfurin da aka zaɓa ya samar da CoA daga dakin gwaje-gwaje na ɓangare na uku. Tabbatar da abun ciki na NRC kuma tabbatar da ya dace da mafi ƙarancin ƙa'idodin tsabta na 98%. Guji samfuran da ba sa bayyana wannan bayanin.
Mataki 3: Tantance bioavailability
Nemo samfuran da suka ambaci fasalulluka masu haɓaka bioavailability. Bincika tsarin isar da aka yi amfani da su da tasirin su. Idan zai yiwu, zaɓi hanyoyin da aka gwada a asibiti don sha da inganci.
Mataki 4: Duba Additives
Bincika jerin abubuwan sinadarai don kowane ƙari ko filaye maras buƙata. Tabbatar cewa samfurin ya ƙunshi ƙarama ko babu abubuwan ƙarawa kuma duk wani abu da aka haɗa yana da lafiya kuma an jera su a fili.
Mataki 5: Kwatanta Farashi
Kwatanta farashin samfuran da aka zaɓa, la'akari da farashin kowane sabis da ƙimar gaba ɗaya. Guji zaɓin masu arha sosai waɗanda zasu iya lalata inganci. Zaɓi samfuran da ke daidaita ma'auni mai kyau tsakanin inganci da araha.
Suzhou Myland Pharm & Nutrition Inc. shine masana'anta mai rijista na FDA wanda ke ba da inganci mai inganci da tsafta nicotinamide riboside chloride foda.
A Suzhou Myland Pharm mun himmatu wajen samar da ingantattun kayayyaki a farashi mafi kyau. An gwada da ƙarfi don tsabta da ƙarfi, mu Nicotinamide Riboside Chloride Foda shine cikakken zaɓi ko kuna son tallafawa lafiyar salula, haɓaka tsarin rigakafi, ko haɓaka lafiyar gabaɗaya.
Tare da shekaru 30 na gwaninta da haɓaka ta hanyar fasaha mai zurfi da ingantattun dabarun R&D, Suzhou Myland Pharm ya haɓaka kewayon samfuran gasa kuma ya zama ƙarin ƙarin ilimin kimiyyar rayuwa, haɗin al'ada da kamfanin sabis na masana'antu.
Bugu da kari, Suzhou Myland Pharm kuma masana'anta ce mai rijista ta FDA. Abubuwan R&D na kamfanin, wuraren samarwa, da kayan aikin nazari na zamani ne kuma masu aiki da yawa, kuma suna iya samar da sinadarai daga milligrams zuwa ton a sikelin, kuma suna bin ka'idodin ISO 9001 da ƙayyadaddun samarwa na GMP.
Tambaya: Menene Nicotinamide Riboside Chloride Foda?
A: Nicotinamide riboside chloride (NRC) wani nau'i ne na bitamin B3 wanda ya sami shahara saboda yuwuwar fa'idodin lafiyar sa, musamman a cikin tallafawa samar da makamashin salula da haɓaka. Ana sayar da NRC sau da yawa a cikin foda, yana sa ya dace ga waɗanda suka fi son tsara adadin su.
Q; Menene Fa'idodin Nicotinamide Riboside Chloride Foda?
A: An yi nazarin NRC don yuwuwarta don tallafawa tsufa mai kyau, haɓaka aikin mitochondrial, da haɓaka juriya da aiki. An kuma yi imani da inganta lafiyar zuciya da jijiyoyin jini da aikin fahimi. Yawancin masu amfani suna ba da rahoton ƙara yawan matakan kuzari da jin daɗin rayuwa gaba ɗaya bayan haɗa NRC cikin ayyukan yau da kullun.
Q：Yaya zan Zabi Babban ingancin Nicotinamide Riboside Chloride Foda?
A: Lokacin siyayya don NRC foda, yana da mahimmanci don ba da fifikon inganci da tsabta. Nemi babban mai siyarwa wanda ke ba da gwaji na ɓangare na uku don tabbatar da samfurin ba shi da gurɓatacce kuma ya dace da ƙa'idodin ƙarfi. Bugu da ƙari, yi la'akari da abubuwa kamar ƙirƙira, hanyoyin masana'antu, da sake dubawa na abokin ciniki don auna ingancin samfurin.
Tambaya: A ina zan iya Siyan Nicotinamide Riboside Chloride Foda?
A: NRC foda yana samuwa daga wasu dillalai na kan layi, shagunan abinci na kiwon lafiya, da kuma shagunan kari na musamman. Lokacin siyan NRC, ba da fifiko ga ƙwararrun masu siyarwa waɗanda ke ba da bayanan gaskiya game da samfuran su, gami da samowa, gwaji, da tallafin abokin ciniki.
Disclaimer: Wannan labarin don cikakken bayani ne kawai kuma bai kamata a fassara shi azaman kowane shawarar likita ba. Wasu daga cikin bayanan post ɗin suna fitowa daga Intanet kuma ba ƙwararru ba ne. Wannan gidan yanar gizon yana da alhakin rarrabuwa, tsarawa da gyara labarai kawai. Manufar isar da ƙarin bayani baya nufin kun yarda da ra'ayoyinsa ko tabbatar da sahihancin abun cikinsa. Koyaushe tuntuɓi ƙwararrun kula da lafiya kafin amfani da kowane kari ko yin canje-canje ga tsarin kula da lafiyar ku.
Lokacin aikawa: Satumba-18-2024
