Taurine muhimmin sinadari ne mai gina jiki kuma yana da wadataccen aminosulfonic acid. Yana yaɗuwa sosai a cikin kyallen jiki da gabobin jiki daban-daban. Ya fi wanzuwa a cikin yanayi na 'yanci a cikin ruwan da ke tsakanin jiki da kuma ruwan da ke cikin ƙwayoyin halitta. Domin ya fara wanzuwa a cikin Named bayan an same shi a cikin bile na bijimin. Ana ƙara Taurine a cikin abubuwan sha na yau da kullun don sake cika kuzari da inganta gajiya.
Kwanan nan, an buga bincike kan taurine a cikin manyan mujallu guda uku na Kimiyya, Kwayoyin Halitta, da Nature. Waɗannan binciken sun bayyana sabbin ayyukan taurine - hana tsufa, inganta tasirin maganin ciwon daji, da kuma hana kiba.
A watan Yunin 2023, masu bincike daga Cibiyar Nazarin Kwayoyin Halittu ta Ƙasa a Indiya, Jami'ar Columbia da ke Amurka, da sauran cibiyoyi sun buga takardu a cikin babbar mujallar ilimi ta duniya ta Kimiyya. Binciken ya nuna cewa ƙarancin ƙwayoyin cuta na taurine shine abin da ke haifar da tsufa. Ƙara sinadarin taurine na iya rage tsufar ƙwayoyin cuta, beraye, da birai, har ma yana iya tsawaita rayuwar beraye masu matsakaicin shekaru da 12%. Cikakkun bayanai: Kimiyya: Ƙarfi fiye da tunanin ku! Taurine kuma zai iya mayar da tsufa da tsawaita tsawon rai?
A watan Afrilun 2024, Farfesa Zhao Xiaodi, Mataimakin Farfesa Lu Yuanyuan, Farfesa Nie Yongzhan, da Farfesa Wang Xin daga Asibitin Xijing na Jami'ar Lafiya ta Soja ta Huɗu sun buga takardu a cikin babbar mujallar ilimi ta duniya ta Cell. Wannan binciken ya gano cewa ƙwayoyin ciwon daji suna fafatawa da ƙwayoyin T na CD8+ don taurine ta hanyar ƙara yawan sinadarin jigilar taurine SLC6A6, wanda ke haifar da mutuwar ƙwayoyin T da gajiya, wanda ke haifar da kubuta daga garkuwar jiki, ta haka yana haɓaka ci gaban ƙari da sake dawowa, yayin da ƙarin Taurine zai iya sake kunna ƙwayoyin T na CD8+ da suka gaji da kuma inganta ingancin maganin ciwon daji.
A ranar 7 ga Agusta, 2024, ƙungiyar Jonathan Z. Long ta Jami'ar Stanford (Dr. Wei Wei shine marubuci na farko) ta buga wani bincike mai taken: PTER wani sinadarin N-acetyl taurine ne wanda ke daidaita ciyarwa da kiba a cikin babbar mujallar ilimi ta duniya ta Nature.
Wannan binciken ya gano sinadarin N-acetyl taurine hydrolase na farko a cikin dabbobi masu shayarwa, PTER, kuma ya tabbatar da muhimmiyar rawar da N-acetyl taurine ke takawa wajen rage yawan cin abinci da kuma hana kiba. A nan gaba, yana yiwuwa a samar da masu hana PTER masu ƙarfi da zaɓaɓɓu don magance kiba.
Ana samun Taurine sosai a cikin kyallen dabbobi masu shayarwa da abinci da yawa kuma ana samunsa a cikin adadi mai yawa a cikin kyallen da ke motsa jiki kamar zuciya, idanu, kwakwalwa, da tsokoki. An bayyana Taurine da cewa yana da ayyukan ƙwayoyin halitta da na jiki na pleiotropic, musamman a cikin mahallin metabolism homeostasis. Ragewar kwayoyin halitta a cikin matakan taurine yana haifar da raguwar tsoka, raguwar ƙarfin motsa jiki, da rashin aiki a cikin mitochondria a cikin kyallen takarda da yawa. Karin Taurine yana rage damuwa a cikin mitochondria, yana inganta ƙarfin motsa jiki, kuma yana danne nauyin jiki.
Binciken halittu da kuma enzyme na metabolism na taurine metabolism sun jawo hankalin bincike mai yawa. A cikin hanyar biosynthesis ta taurine ta ciki, cysteine yana narkewa ta hanyar cysteine dioxygenase (CDO) da cysteine sulfinate decarboxylase (CSAD) don samar da hypotaurine, wanda daga baya Oxidation ta flavin monooxygenase 1 (FMO1) yana samar da taurine. Bugu da ƙari, cysteine na iya samar da hypotaurine ta hanyar hanyar madadin cysteamine da cysteamine dioxygenase (ADO). A ƙasan taurine da kanta akwai wasu metabolites na taurine na biyu, gami da taurocholate, tauramidine, da N-acetyl taurine. Enzyme ɗaya tilo da aka sani don haɓaka waɗannan hanyoyin ƙasa shine BAAT, wanda ke haɗa taurine da bile acyl-CoA don samar da taurocholate da sauran gishirin bile. Baya ga BAAT, ba a tantance asalin ƙwayoyin enzymes na wasu enzymes da ke shiga tsakani na metabolism na taurine na biyu ba tukuna.
N-acetyltaurine (N-acetyl taurine) wani abu ne mai ban sha'awa amma wanda ba a yi nazari sosai ba a fanninsa na biyu na taurine. Matakan N-acetyl taurine a cikin ruwan halittu ana sarrafa su ta hanyar rikice-rikice da yawa na jiki waɗanda ke ƙara yawan kwararar taurine da/ko acetate, gami da motsa jiki na jurewa, shan barasa, da ƙarin taurine mai gina jiki. Bugu da ƙari, N-acetyltaurine yana da kamanceceniya da tsarin sinadarai zuwa ƙwayoyin sigina, gami da acetylcholine mai neurotransmitter da kuma acyltaurine mai tsayi wanda ke daidaita sukari na jini, yana nuna cewa yana iya aiki azaman metabolite na sigina. Samfurin yana aiki. Duk da haka, ba a fayyace yanayin halitta, lalacewar, da yuwuwar ayyukan N-acetyl taurine ba.
A cikin wannan sabon binciken, ƙungiyar binciken ta gano PTER, wani enzyme mara aure wanda ba a san aikinsa ba, a matsayin babban sinadarin N-acetyl taurine hydrolase na dabbobi masu shayarwa. A cikin vitro, PTER mai sake haɗawa ya nuna ƙaramin kewayon substrate da manyan ƙuntatawa. A cikin N-acetyl taurine, ana haɗa shi da ruwa zuwa taurine da acetate.
Kashe kwayar halittar Pter a cikin beraye yana haifar da asarar aikin N-acetyl taurine hydrolytic gaba ɗaya a cikin kyallen takarda da kuma ƙaruwar yawan N-acetyl taurine a cikin kyallen takarda daban-daban.
Wurin PTER na ɗan adam yana da alaƙa da ma'aunin nauyin jiki (BMI). Ƙungiyar binciken ta ƙara gano cewa bayan ƙarfafawa tare da ƙaruwar matakan taurine, beraye masu fama da cutar Pter sun nuna raguwar yawan cin abinci kuma suna da juriya ga kiba da abinci ke haifarwa. da kuma inganta yanayin glucose. Ƙarin N-acetyl taurine ga beraye masu kiba na daji shi ma ya rage yawan cin abinci da nauyin jiki ta hanyar da ta dogara da GFRAL.
Waɗannan bayanai suna sanya PTER a cikin babban enzyme node na taurine na metabolism na biyu kuma suna bayyana rawar da PTER da N-acetyl taurine ke takawa wajen sarrafa nauyi da daidaita kuzari.
Gabaɗaya, wannan binciken ya gano sinadarin acetyl taurine hydrolase na farko a cikin dabbobi masu shayarwa, PTER, kuma ya tabbatar da muhimmiyar rawar da acetyl taurine ke takawa wajen rage yawan cin abinci da kuma hana kiba. A nan gaba, ana sa ran za a samar da masu hana PTER masu ƙarfi da zaɓaɓɓu don magance kiba.
Bayanin Kariya: Wannan labarin don bayanai ne kawai kuma bai kamata a fassara shi a matsayin wata shawara ta likita ba. Wasu daga cikin bayanan da aka wallafa a shafin yanar gizo sun fito ne daga Intanet kuma ba ƙwararru ba ne. Wannan gidan yanar gizon yana da alhakin tsarawa, tsarawa da kuma gyara labarai kawai. Manufar isar da ƙarin bayani ba yana nufin cewa kun yarda da ra'ayoyinsa ko tabbatar da sahihancin abubuwan da ke ciki ba. Kullum ku tuntuɓi ƙwararren likita kafin amfani da duk wani kari ko yin canje-canje ga tsarin kula da lafiyar ku.
Lokacin Saƙo: Agusta-12-2024
