A cikin 'yan shekarun nan, an sami karuwar sha'awa ga mahaɗan dabi'a waɗanda zasu iya haɓaka lafiyar gaba ɗaya da jin daɗin rayuwa. Urolithin A da urolithin B sune mahadi na halitta guda biyu da aka samo daga ellagitannins da ake samu a cikin wasu 'ya'yan itatuwa da kwayoyi. Su anti-mai kumburi, antioxidant, da tsoka-ginin Properties sa su ban sha'awa mahadi don inganta gaba ɗaya lafiya. Ko da yake urolitin A da urolithin B suna da kaddarorin da ke da alaƙa, suna da wasu bambance-bambance masu mahimmanci.
Urolithin A da B su ne metabolites waɗanda ke samuwa a cikin jikin mutum ta hanyar halitta sakamakon narkewar wasu abubuwan abinci, musamman ellagitannins. Ellagitannins suna samuwa a cikin 'ya'yan itatuwa da kwayoyi daban-daban, ciki har da rumman, strawberries, raspberries, blackberries, da walnuts. Koyaya, kaɗan ne kawai na yawan jama'a ke da ƙwayoyin hanji waɗanda ke iya canza ellagitannins zuwa urolithins, suna yin matakan urolithin a cikin mutane masu canzawa sosai.
Ga wadanda ke da wahalar biyan bukatun magnesium ta hanyar cin abinci kadai, abubuwan da ake amfani da su na magnesium na iya amfanar lafiya ta hanyoyi da yawa kuma sun zo cikin nau'i kamar magnesium oxide, magnesium threonate, magnesium taurate, da magnesium glycinate. Koyaya, ana ba da shawarar tuntuɓar ƙwararrun kiwon lafiya kafin fara kowane tsarin kari don gujewa yuwuwar mu'amala ko rikitarwa.
Urolithin A shine mafi yawan kwayoyin halitta a cikin dangin urolithin, kuma an yi nazarin abubuwan da ke tattare da antioxidant da anti-inflammatory. Nazarin ya nuna cewa urolithin A na iya inganta aikin mitochondrial kuma ya hana lalacewar tsoka. Bugu da ƙari, binciken ya nuna cewa urolithin A zai iya hana yaduwar kwayar halitta kuma ya haifar da mutuwar kwayar halitta a cikin nau'o'in kwayoyin cutar kansa.
Urolithin B ya ja hankalin masu bincike don ikonsa na inganta lafiyar hanji da rage kumburi. Bincike ya nuna cewa urolithin B na iya haɓaka bambance-bambancen microbial na gut da rage cytokines masu kumburi kamar interleukin-6 da ƙari necrosis factor alpha. Bugu da ƙari, an gano urolithin B yana da abubuwan da za su iya kare lafiyar jiki, tare da nazarin da ke nuna cewa zai iya taimakawa wajen hana cututtuka na neurodegenerative kamar Parkinson's da Alzheimer's.
Ko da yake urolitin A da urolithin B suna da kaddarorin da ke da alaƙa, suna da bambance-bambance masu mahimmanci. Misali, urolithin A an nuna ya fi tasiri a matsayin maganin kumburi da antioxidant fiye da urolithin B. Urolithin B, a daya bangaren, an gano ya fi tasiri wajen hana matsalolin da ke da alaka da kiba, kamar juriya na insulin da adipocyte. bambanta.
Hanyoyin aikin urolitin A da urolithin B ma sun bambanta. Urolithin A yana kunna peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) hanya, wanda ke taka rawa a cikin biogenesis na mitochondrial, yayin da urolithin B yana haɓaka hanyar AMP-activated protein kinase (AMPK), wanda ke shiga cikin makamashi homeostasis. Wadannan hanyoyi suna ba da gudummawa ga tasirin lafiyar lafiyar waɗannan mahadi.
●Anti-mai kumburi Properties
An san kumburi na yau da kullun yana ba da gudummawa ga cututtuka da yawa. An nuna Urolithin A yana da kaddarorin anti-mai kumburi mai ƙarfi, yana rage samar da ƙwayoyin kumburi. Ta hanyar murkushe kumburi, yana iya yuwuwar taimakawa sarrafa yanayi na yau da kullun kamar arthritis, cututtukan zuciya, da wasu nau'ikan ciwon daji.
●Lafiyar tsoka da Ƙarfi
Yayin da muke tsufa, asarar tsoka na kwarangwal ya zama damuwa mai mahimmanci. An gano Urolitin A don haɓaka haɓakar ƙwayoyin tsoka da haɓaka aikin tsoka, haɓaka lafiyar tsoka da ƙarfi. Wannan yana ɗaukar alƙawarin ga daidaikun mutane waɗanda ke neman adana yawan ƙwayar tsoka da yaƙi da raguwar tsoka mai alaƙa da shekaru.
●Mitochondrial Lafiya da Tsawon Rayuwa
Urolithin A yana nuna tasiri mai ƙarfi akan mitochondria, sau da yawa ana magana da shi azaman ƙarfin sel ɗin mu. Yana haifar da wani tsari da ake kira mitophagy, wanda ya haɗa da zaɓin cirewar mitochondria mai lalacewa. Ta hanyar haɓaka aikin mitochondrial lafiya, urolithin A na iya ba da gudummawa ga tsawon rai da kuma kariya daga yanayin da suka shafi shekaru kamar cututtukan neurodegenerative.
●Ayyukan Antioxidant
Urolithin B shine antioxidant mai ƙarfi wanda ke taimakawa kawar da radicals masu cutarwa a cikin jiki. radicals free radicals ne mai matukar amsawa kwayoyin da za su iya ba da gudummawa ga lalacewar salula da damuwa na oxidative, da ke tattare da cututtuka daban-daban. Ayyukan antioxidant na Urolithin B na taimakawa kare kwayoyin mu daga irin wannan lalacewa kuma yana iya rage haɗarin cututtuka na yau da kullum.
●Lafiyar Gut da Modulation Microbiome
Gut ɗinmu yana taka muhimmiyar rawa a cikin lafiyarmu gaba ɗaya, kuma urolithin B ya fito a matsayin babban ɗan wasa don kiyaye microbiome mai lafiya. Yana inganta haɓakar beneficial kwayoyin cuta da kuma hana ci gaban cutarwa kwayoyin cuta, don haka inganta daidaita microbial yanayi. Mafi kyawun microbiome na gut yana da alaƙa da ingantaccen narkewa, aikin rigakafi, da jin daɗin tunani.
●Inganta lafiyar tsoka
An nuna Urolithin B don tayar da mitochondrial autophagy, tsarin salula wanda ke taimakawa wajen kawar da mitochondria mai lalacewa daga sel. Wannan tsari yana taimakawa wajen inganta lafiyar tsoka da aiki gabaɗaya, yana mai da shi ƙarin ƙari ga waɗanda ke neman haɓaka aikin jiki. Ɗaya daga cikin binciken ya gano cewa urolithin B yana inganta aikin tsoka da ƙarfi a cikin mice da mutane.
Ana samar da Urolithins a cikin jikinmu bayan cin abinci da ke dauke da ellagitannins. Manyan hanyoyin abinci na ellagitannins sun hada da:
a) Ruman
Ruman yana ɗaya daga cikin mafi kyawun tushen abinci na ellagitannins, waɗanda ake canza su zuwa urolithin A da urolithin B ta ƙwayoyin hanji. Cin 'ya'yan itacen rumman, ruwan 'ya'yan itace, ko kayan miya na iya haɓaka ci na waɗannan mahadi masu ƙarfi, haɓaka lafiyar salula da yin tasirin anti-mai kumburi.
b) Berries
Daban-daban berries irin su strawberries, raspberries, da blackberries sun ƙunshi babban matakan ellagitannins. Nazarin ya nuna cewa cinye waɗannan 'ya'yan itatuwa masu ban sha'awa yana inganta samar da urolithin A da urolithin B a cikin hanji. Ƙara berries a cikin abincinku ba kawai yana haɓaka dandano ba amma yana ba da fa'idodin kiwon lafiya na dogon lokaci.
c) Kwayoyi
Kwayoyi, musamman gyada da pecans, sune tushen tushen ellagitannins. Bugu da ƙari, suna cike da lafiyayyen kitse, fiber, da sauran muhimman abubuwan gina jiki. Ciki har da goro a cikin abincin ku na yau da kullun ba wai kawai yana ba da urolithin A da B ba har ma yana ba da fa'idodin kiwon lafiya da yawa ga zuciya, ƙwaƙwalwa, da kuma jin daɗin rayuwa gaba ɗaya.
d) ruwan inabi masu tsufa
Ko da yake yana iya zama abin mamaki, matsakaiciyar amfani da ruwan inabin jan itacen oak kuma na iya taimakawa wajen samar da urolithin. Abubuwan da ke cikin ganga na itacen oak da aka yi amfani da su don tsufa ana iya fitar da su a lokacin tsarin tsufa, suna ba da ruwan inabi tare da ellagitannins. Koyaya, yana da mahimmanci a tuna cewa yawan shan barasa yana da illa ga lafiyar jiki, don haka daidaitawa shine mabuɗin.
e) Tsirrai masu arzikin Ellagitannin
Tare da rumman, wasu tsire-tsire kamar itacen oak, strawberries, da ganyen itacen oak suna da yawa a cikin ellagitannins. Haɗa waɗannan tsire-tsire a cikin abincin ku na iya taimakawa haɓaka matakan urolithin A da urolithin B a cikin jikin ku, tallafawa lafiyar salula da inganta lafiyar gaba ɗaya.
Don haɗawaurolitin A da B a cikin salon ku, hanya ɗaya mai dacewa ita ce cin abinci mai wadatar ellagitannins. Ruman, strawberries, raspberries, da walnuts sune kyakkyawan tushe.
Duk da haka, yana da mahimmanci a lura cewa abun ciki na ellagitannin ya bambanta a cikin kowane 'ya'yan itace, kuma ba kowa ba ne yana da microbiota guda ɗaya wanda zai iya canza ellagitannins zuwa urolithins. Saboda haka, wasu mutane ba za su iya samar da urolitin ba da kyau daga waɗannan hanyoyin abinci. kari wani zaɓi ne don tabbatar da isasshen abinci na urolitin A da B.
Tambaya: Ta yaya Urolithin A da Urolithin B ke inganta lafiyar mitochondrial?
A: Urolithin A da Urolithin B suna kunna hanyar salula da ake kira mitophagy, wanda ke da alhakin cire mitochondria da ya lalace daga sel. Ta hanyar haɓaka mitophagy, waɗannan mahadi suna taimakawa kiyaye yawan mitochondrial lafiya, wanda ke da mahimmanci don samar da kuzari da aikin salula gabaɗaya.
Tambaya: Za a iya samun Urolithin A da Urolithin B ta hanyar kari?
A: Ee, Urolithin A da Urolithin B ana samun su a kasuwa. Koyaya, yana da mahimmanci a lura cewa tasiri da amincin waɗannan abubuwan kari na iya bambanta. Ana ba da shawarar yin shawara tare da ƙwararrun kiwon lafiya kafin fara kowane sabon kayan abinci.
Disclaimer: Wannan labarin don dalilai ne na bayanai kawai kuma bai kamata a yi la'akari da shawarar likita ba. Koyaushe tuntuɓi ƙwararrun kiwon lafiya kafin amfani da kowane kari ko canza tsarin kula da lafiyar ku.
Lokacin aikawa: Satumba-13-2023
