Me kuke buƙatar sani game da palmitoylethanolamide (PEA)?

Palmitoylethanolamide (PEA) wani fatty acid amide ne wanda ke faruwa a zahiri wanda ya ja hankali ga fa'idodin lafiyar sa. Ana samun wannan fili a cikin kyallen takarda daban-daban a cikin jiki, kuma bincike ya nuna cewa palmitamideethanol (PEA) na iya rage kumburi, rage zafi, kuma yana iya inganta lafiyar hanji da jinkirta tsufa. Yana iya samun fa'idodin kiwon lafiya iri-iri. Abubuwan da ke biyowa zasu bincika fa'idodin kiwon lafiya na palmitoylethanolamide (PEA), yadda yake aiki akan jikin ɗan adam, da kuma yadda ake samun palmitoylethanolamide mai inganci (PEA).

Menene palmitoylethanolamide (PEA)?

Palmitoylethanolamide (PEA) wani abu ne na halitta endocannabinoid-kamar fili wanda aka sani don maganin analgesic na yau da kullun da kaddarorin anti-mai kumburi. Baya ga hadawa da jiki, ana samun PEA a cikin abinci iri-iri da suka hada da: cuku, gwaiduwa kwai, nama, madara, gyada, lecithin soya.

ka sani? Lokacin da jiki ya gamu da damuwa, kamar rauni ko kumburi, matakan PEA suna daidaita don kula da homeostasis na salula.

Ta yaya palmitoylethanolamide ke shafar jikin mutum?

Har yanzu masana kimiyya ba su fahimci tsarin aikin palmitoylethanolamide ba. Duk da haka, mun yi nisa, godiya ga Farfesa Rita Levi-Montalcini, wanda a cikin 1992-1996 ya bayyana tsarin aikin palmitoylethanolamide. Tun daga wannan lokacin, ta ci gaba da nazarin tasirin palmitoylethanolamide akan ciwon neuropathic da allergies.

Palmitoylethanolamide na iya kawo manyan fa'idodin kiwon lafiya guda huɗu ga mutane:

●Sake amsa mai kumburi.

●Rage mast cell kunnawa (allergy).

● Ƙarfafa aikin tsarin hemp na endogenous.

● Kunna takamaiman masu karɓa a cikin jiki.

Ta yaya PEA ke aiwatar da tasirin anti-mai kumburi da analgesic?

Amfanin kiwon lafiya na PEA sun haɗa da tasiri akan ƙwayoyin rigakafi waɗanda ke sarrafa kumburi, musamman a cikin kwakwalwa. PEA na iya taimakawa rage samar da abubuwa masu kumburi. Koyaya, PEA galibi tana aiki akan masu karɓa akan sel, waɗanda ke sarrafa sassa daban-daban na aikin tantanin halitta. Ana kiran waɗannan masu karɓan PPARs. PEA da sauran mahadi waɗanda ke taimakawa kunna PPAR na iya rage zafi kuma suna iya haɓaka metabolism ta hanyar ƙona kitse, ƙananan ƙwayar triglycerides, ƙara yawan ƙwayar cholesterol HDL, inganta sarrafa sukari na jini, da kuma taimakawa asarar nauyi.

Amfanin Palmitoylethanolamide

Saboda tasirin analgesic da anti-mai kumburi, bincike ya nuna cewa PEA na iya taimakawa tare da nau'ikan yanayin da ke da alaƙa da zafi, irin su fibromyalgia, sciatica, da osteoarthritis.

1. Rage zafi da amsa mai kumburi

Ciwo na yau da kullum matsala ce mai tsanani da ke addabar marasa lafiya a duniya, kuma yayin da yawan jama'a ke da shekaru, wannan matsala za ta zama mai mahimmanci. Ɗaya daga cikin ayyukan palmitoylethanolamide shine cewa yana iya taimakawa rage zafi da kumburi. palmitoylethanolamide yana hulɗa tare da CB1 da CB2 masu karɓa, waɗanda ke da mahimmancin sassan tsarin hemp na endogenous. Wannan tsarin yana da alhakin kiyaye homeostasis ko daidaituwa a cikin jiki.

Lokacin da wani rauni ko mai kumburi ya faru, jiki yana sakin mahadi na hemp na endogenous don taimakawa sarrafa martanin rigakafi. palmitoylethanolamide na iya taimakawa haɓaka matakan hemp na endogenous a cikin jiki, ta haka yana kawar da zafi da kumburi.

Bugu da ƙari, palmitoylethanolamide na iya rage sakin sinadarai masu kumburi da rage gabaɗayan martanin kumburin ƙwayoyin cuta. Wadannan tasirin suna sa palmitoylethanolamide ya zama kayan aiki mai yuwuwa don taimakawa sarrafa raɗaɗi da martani mai kumburi. Nazarin ya nuna cewa palmitoylethanolamide na iya zama mai tasiri ga ciwon sciatica da ciwon ramin carpal.

2. Fibromyalgia

Yawancin karatu sun nuna cewa PEA na iya taimakawa wajen rage alamun fibromyalgia, cututtukan cututtuka na kullum wanda ke haifar da ciwo mai yawa. Lokacin da aka yi amfani da shi azaman haɗin kai ga hanyoyin kwantar da hankali na al'ada, cin abinci na PEA yana rage yawan zafi kuma yana inganta yanayin rayuwa a tsawon lokaci. Bisa ga binciken daya, shan PEA na tsawon watanni uku ya rage yawan ciwo a cikin mutanen da ke da fibromyalgia.

3. Ciwon baya

Binciken farko yana nuna yiwuwar tasiri na PEA don ciwon baya. Wani bincike na 2017 ya nuna cewa PEA ta kara rage yawan ciwo a cikin marasa lafiya tare da ciwon ciwon baya na baya.

Mutanen da ke fama da sciatica, ciwon da ke tasowa daga ƙananan baya zuwa ɗaya ko biyu kafafu, na iya samun sauƙi bayan shan PEA. Wani bazuwar, makafi biyu, gwaji mai sarrafa wuribo ya yi nazari akan tasirin PEA mai girma da ƙaranci tare da placebo. An rage jin zafi fiye da 50% a cikin rukuni mai girma. Ko da yake ƙananan PEA ba su cimma matsayi ɗaya na jin zafi ba kamar babban kashi, duka allurai sun fi tasiri fiye da placebo.

4. Osteoarthritis

PEA na iya zama da amfani ga mutanen da ke fama da osteoarthritis, cutar da ke nuna lalacewa na guringuntsi na haɗin gwiwa da kashi. Mahalarta binciken guda ɗaya waɗanda suka karɓi PEA sun sami ci gaba mai mahimmanci a Western Ontario da McMaster Jami'o'in Osteoarthritis Index (WOMAC) idan aka kwatanta da rukunin placebo. WOMAC takarda ce da aka tsara don tantance yanayin da alamomi (misali, zafi, taurin kai, aikin jiki) a cikin marasa lafiya da ke da gwiwa da hip osteoarthritis.

Wani binciken da ya shafi marasa lafiya tare da ciwo na wucin gadi na wucin gadi (TMJ) da ke hade da osteoarthritis ya nuna cewa ƙarin PEA ya inganta ingantaccen zafi bayan kwanaki 14 idan aka kwatanta da ibuprofen. Ƙungiyar da aka ba da PEA don kwanakin 14 ya nuna babban ci gaba a cikin iyakar bude baki (ma'auni na jin zafi) fiye da kungiyar ibuprofen.

5. Ciwon Neuropathic

Nazarin shari'ar farko da gwajin dabba sun nuna cewa PEA na iya taimakawa tare da ciwon neuropathic (wanda ya haifar da lalacewa ga jijiyoyi da ke dauke da sakonni tsakanin kwakwalwa da kashin baya), musamman a cikin mutanen da ke fama da ciwo na tunnel na carpal, ciwon sukari neuropathy, chemotherapy Mutanen da ke da neuropathy na gefe, na kullum. zafi pelvic, da kuma zafi hade da bugun jini da mahara sclerosis. Ana buƙatar ƙarin gwaje-gwaje na asibiti don sanin ingancin PEA don magance ciwon neuropathic.

6. Lafiyayyan tsufa

Jinkirta tsarin tsufa wata manufa ce mai amfani da masana kimiyya da yawa a duniya ke bi. Palmitoylethanolamide ana ɗaukarsa ƙarin maganin tsufa wanda zai iya taimakawa kare sel daga lalacewar iskar oxygen, wanda shine babban dalilin tsufa.

Lokacin da sel suka fallasa zuwa ayyukan tsattsauran ra'ayi da yawa, halayen oxidative na iya faruwa, wanda zai haifar da mutuwar kwayar halitta. Yin amfani da abinci mara kyau, shan taba, da sauran abubuwan da suka shafi muhalli irin su gurɓataccen iska kuma yana ƙara yawan lalacewar oxidative.Palmitoylethanolamide na iya hana wannan lalacewa ta hanyar cire radicals kyauta da rage yawan amsawar kumburi a cikin jiki.

Bugu da ƙari, an nuna palmitoylethanolamide ethanol don yin yuwuwar haɓaka samar da collagen da sauran mahimman sunadaran fata. Sabili da haka, yana iya rage bayyanar wrinkles da layi mai kyau, yana aiki azaman mai kariya daga cikin sel.

Suzhou Myland Pharm & Nutrition Inc. shine masana'anta mai rijista na FDA wanda ke ba da inganci mai inganci da tsaftar Palmitoylethanolamide (PEA).

A Suzhou Myland Pharm mun himmatu wajen samar da ingantattun kayayyaki a farashi mafi kyau. Our Palmitoylethanolamide (PEA) foda an gwada shi da ƙarfi don tsabta da ƙarfi, yana tabbatar da samun ƙarin ingantaccen kari da za ku iya dogara. Ko kuna son tallafawa lafiyar salula, haɓaka tsarin rigakafi, ko haɓaka lafiyar gabaɗaya, Palmitoylethanolamide (PEA) foda shine zaɓi mafi kyau.

Tare da shekaru 30 na gwaninta da haɓaka ta hanyar fasaha mai zurfi da ingantattun dabarun R&D, Suzhou Myland Pharm ya haɓaka kewayon samfuran gasa kuma ya zama ƙarin ƙarin ilimin kimiyyar rayuwa, haɗin al'ada da kamfanin sabis na masana'antu.

Bugu da kari, Suzhou Myland Pharm kuma masana'anta ce mai rijista ta FDA. Abubuwan R&D na kamfanin, wuraren samarwa, da kayan aikin nazari na zamani ne kuma masu aiki da yawa, kuma suna iya samar da sinadarai daga milligrams zuwa ton a sikelin, kuma suna bin ka'idodin ISO 9001 da ƙayyadaddun samarwa na GMP.