N-Boc-O-Benzyl-D-serine foda manufacturer CAS No.: 47173-80-8 98% tsarki min. don Matsakaici
Ma'aunin Samfura
Sunan samfur | N-Boc-O-Benzyl-D-serine |
Wani suna | N-Boc-O-benzyl-D-serine; Boc-O-benzyl-D-serine; O-Benzyl-N-(tert-butoxycarbonyl)-D-serine; Boc-(R) -2-amino-3-benzyloxypropionic acid; Boc-D-Ser(Bzl)-OH;Nat.-Boc-O-benzyl-D-serine; N-tert-butyloxycarbonyl-O-benzyl-D-serine; Nalpha-t-butoxycarbonyl-O-benzyl-D-serine; |
CAS No. | 47173-80-8 |
Tsarin kwayoyin halitta | Saukewa: C15H21NO5 |
Nauyin kwayoyin halitta | 295.33 |
Tsafta | 98% |
Shiryawa | 1kg/bag;25kg/drum |
Aikace-aikace | Matsakaici |
Gabatarwar samfur
N-Boc-O-Benzyl-D-serine wani fili ne wanda ya sami kulawa mai mahimmanci a fagen ilimin kimiyyar kwayoyin halitta da bincike na magunguna. Wannan fili, wanda kuma aka sani da Boc-D-serine, ya samo asali ne daga amino acid D-serine kuma ana amfani dashi sosai wajen hada magunguna daban-daban da kwayoyin halittu masu rai. N-Boc-O-Benzyl-D-serine fari ne zuwa fari-fari crystalline foda wanda yake da ɗan narkewa cikin ruwa kuma yana narkewa a cikin kaushi na halitta kamar methanol da ethanol. Ya samo asali ne daga D-serine, wanda shine amino acid mara-proteinogenic wanda ke taka muhimmiyar rawa a cikin tsarin juyayi na tsakiya azaman mai haɗin gwiwa na mai karɓar N-methyl-D-aspartate (NMDA). N-Boc (tert-butoxycarbonyl) da O-Benzyl kungiyoyin a cikin fili suna aiki a matsayin ƙungiyoyi masu kariya, suna ba da izinin yin amfani da amino acid a lokacin haɗin sinadarai.N-Boc-O-Benzyl-D-serine an fara amfani da shi azaman toshe ginin a cikin kira na peptides da peptidomimetics. Peptides gajerun sarƙoƙi ne na amino acid waɗanda ke taka rawa iri-iri a cikin hanyoyin nazarin halittu kuma suna da sha'awar gano magunguna da haɓakawa. Ta hanyar haɗa N-Boc-O-Benzyl-D-serine a cikin jerin peptide, masu ilimin chemists na iya daidaita kaddarorin da ayyukan peptides da aka samu, suna mai da shi kayan aiki mai mahimmanci a cikin ƙirar sabbin magunguna. Bugu da ƙari kuma, ana amfani da N-Boc-O-Benzyl-D-serine a cikin shirye-shiryen masu tsaka-tsakin magunguna da kayan aikin magunguna (APIs). Matsakaicinsa na reactivity da dacewa tare da halayen sinadarai iri-iri sun sa ya zama abin da ake nema a cikin haɗaɗɗun kwayoyin halitta masu rikitarwa tare da yuwuwar warkewa.
Siffar
(1) Babban tsabta: N-Boc-O-Benzyl-D-serine na iya samun samfurori masu tsabta ta hanyar tsaftace tsarin samarwa. Babban tsabta yana nufin mafi kyawun yanayin rayuwa da ƙarancin halayen halayen.
(2) Tsaro: Babban aminci, 'yan mummunan halayen.
(3) Kwanciyar hankali: N-Boc-O-Benzyl-D-serine yana da kwanciyar hankali mai kyau kuma yana iya kula da ayyukansa da tasiri a ƙarƙashin yanayi daban-daban da yanayin ajiya.
Aikace-aikace
Haɗin N-Boc-O-Benzyl-D-serine cikin ƙwayoyin ƙwayoyi an nuna don ba da kyawawan kaddarorin pharmacokinetic da pharmacodynamic. Peptidomimetics da aka samo daga N-Boc-O-Benzyl-D-serine sun nuna ingantaccen kwanciyar hankali, bioavailability, da ƙayyadaddun manufa, yana mai da su 'yan takara masu ba da shawara don maganin cututtuka daban-daban, ciki har da ciwon daji, cututtuka, da cututtuka na jijiyoyin jini. Bugu da ƙari, iyawar. don zaɓar gyaggyarawa tsarin N-Boc-O-Benzyl-D-serine yana ba da izinin daidaitawa na masu neman magani, inganta ingancin su da bayanan martaba.